Zepbound and Wegovy are approved by the FDA for weight loss, while Ozempic is approved for the treatment of type 2 diabetes, but can be prescribed off-label for weight loss, if appropriate.

The main difference between these medications is the active ingredient. Ozempic and Wegovy use semaglutide, while Zepbound uses tirzepatide. Tirzepatide is a dual-action GLP-1 and GIP, meaning it works by activating two receptors to curb nausea and regulate your metabolism, helping you feel full faster and longer. In comparison, semaglutide only activates the GLP-1 receptor. buy zepbound online

What’s the difference between Zepbound pens and vials?

Zepbound pens and vials are the exact same FDA-approved medication, but are available in different dosage forms and strengths. This means that when the medication is used in the same dose – whether taken via a vial or pen – it has the same efficacy and side effects. On average, people on Zepbound lose 20% of their weight in a year.*

Key differences:

• Zepbound vials are administered with a syringe, while Zepound pens are prefilled.

• Zepbound vials are available in 2.5 mg, 5 mg, 7.5 mg, and 10 mg doses. Zepbound pens include those doses plus 12.5 mg and 15 mg.

• Zepbound vials can be shipped conveniently and directly to you from the LillyDirect partner pharmacy, while Zepbound pens can only be fulfilled through your preferred pharmacy.

• Zepbound vials are only available as a cash pay offering, and are not eligible for insurance coverage. Zepbound pens are available as a cash pay offering or through insurance coverage.

*Price compared to the list price of Zepbound autoinjector pen, without applying insurance or savings cards. Zepbound vials are a cash-pay offering only. Full weight loss results are seen at about 1 year, when combined with diet and exercise.

Safety info: GLP-1 medications are used to treat obesity or overweight (with weight-related problems), along with diet and exercise. They may have serious side effects, including possible thyroid tumors. Do not use if you or your family have a history of a type of thyroid cancer called MTC or MEN 2.